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CLEARPLASMA
​The ClearPlasma device is a non-pyrogenic, sterile, single-use device designed to remove plasminogen from blood products. It utilizes the chemical affinity of plasminogen to a specific ligand through its binding sites. As plasma passes through the resin bed, plasminogen encounters the covalently bound ligand and binds to it. The plasminogen-depleted plasma then flows through the device and is collected in a new plasma bag, ready for transfusion.
plas free
AAPC-300
Plas-Free’s Ammonia Adsorption Plasma Column (AAPC-300) device is a non-pyrogenic, sterile, single-use device designed to remove ammonia from the blood stream. The AAPC-300 effectively and specifically extracts ammonia from plasma fraction, thus enabling the reduction of ammonia levels during hepatic encephalopathy (HE). Neurological injury is non-reversible, thus time is critical in the treatment of hyperammonemia. The APPC-300 can reduce the levels of ammonia in less than 1.5 hours thereby preventing significant accumulated neurologic injury. This contrasts with the pharmacokinetics of drugs that can take few hours and subsequently cause additional neurologic injury.
INNOVATIVE PLASMA FILTRATION TECHNOLOGY
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement no 882231